Fig. 3. miR-106b inhibitor regulated JAK1/STAT3 Signaling Pathway. (a) Detection of JAK/STAT pathway related protein levels after cells treated with or without miR-106b inhibitor. (b, c) The expression levels of pJAK1 and pSTAT3 were detected following treatment with with miR-106b inhibitor and/or PLVX-ALEX1. *P<0.05 versus control, **P<0.01 versus control. (d) Cell apoptosis was detected following treatment with miR-106b inhibitor and/or PLVX-JAK1. **P<0.01 versus control. # P<0.05 versus miR-106b inhibitor treatment. (e, f) Detection of apoptotic proteins after cells treated with miR-106b inhibitor and/or PLVX-JAK1. *P<0.05 versus miR-106b inhibitor treatment.